Department of Radiology
Found 15 results
Filters: Author is Crystal, Ronald G  [Clear All Filters]
2023
Rosenberg JB, Fung EK, Dyke J, De BP, Lou H, Kelly J, Reejhsinghani L, Arbona RJRicart, Sondhi D, Kaminsky SM et al..  2023.  Positron Emission Tomography Quantitative Assessment of Off-Target Whole-Body Biodistribution of I-124-labeled Adeno-associated Virus Capsids Administered to Cerebral Spinal Fluid.. Hum Gene Ther.
2021
Rosenberg JB, Chen A, De BP, Dyke JP, Ballon DJ, Monette S, Arbona RJRicart, Kaminsky SM, Crystal RG, Sondhi D.  2021.  Safety of Direct Intraparenchymal AAVrh.10-Mediated Central Nervous System Gene Therapy for Metachromatic Leukodystrophy.. Hum Gene Ther. 32(11-12):563-580.
2020
Ballon DJ, Rosenberg JB, Fung EK, Nikolopoulou A, Kothari P, De BP, He B, Chen A, Heier LA, Sondhi D et al..  2020.  Quantitative Whole-Body Imaging of I-124-Labeled Adeno-Associated Viral Vector Biodistribution in Nonhuman Primates.. Hum Gene Ther. 31(23-24):1237-1259.
Sondhi D, Kaminsky SM, Hackett NR, Pagovich OE, Rosenberg JB, De BP, Chen A, Van de Graaf B, Mezey JG, Mammen GW et al..  2020.  Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing .. Sci Transl Med. 12(572)
2018
Rosenberg JB, Kaplitt MG, De BP, Chen A, Flagiello T, Salami C, Pey E, Zhao L, Arbona RJRicart, Monette S et al..  2018.  AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease.. Hum Gene Ther Clin Dev. 29(1):24-47.
Sindelar M, Dyke JP, Deeb RS, Sondhi D, Kaminsky SM, Kosofsky BE, Ballon DJ, Crystal RG, Gross SS.  2018.  Untargeted Metabolite Profiling of Cerebrospinal Fluid Uncovers Biomarkers for Severity of Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2, Batten Disease).. Sci Rep. 8(1):15229.
2016
Hicks MJ, Chiuchiolo MJ, Ballon D, Dyke JP, Aronowitz E, Funato K, Tabar V, Havlicek D, Fan F, Sondhi D et al..  2016.  Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma.. PLoS One. 11(10):e0162978.
2015
Hicks MJ, Funato K, Wang L, Aronowitz E, Dyke JP, Ballon DJ, Havlicek DF, Frenk EZ, De BP, Chiuchiolo MJ et al..  2015.  Genetic modification of neurons to express bevacizumab for local anti-angiogenesis treatment of glioblastoma.. Cancer Gene Ther. 22(1):1-8.
2014
Santillan A, Rubin DG, Foley CP, Sondhi D, Crystal RG, Y Gobin P, Ballon DJ.  2014.  Cannulation of the internal carotid artery in mice: a novel technique for intra-arterial delivery of therapeutics.. J Neurosci Methods. 222:106-10.
Foley CP, Rubin DG, Santillan A, Sondhi D, Dyke JP, Crystal RG, Y Gobin P, Ballon DJ.  2014.  Intra-arterial delivery of AAV vectors to the mouse brain after mannitol mediated blood brain barrier disruption.. J Control Release. 196:71-78.
2013
Maoz A, Hicks MJ, Vallabhjosula S, Synan M, Kothari PJ, Dyke JP, Ballon DJ, Kaminsky SM, De BP, Rosenberg JB et al..  2013.  Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter.. Neuropsychopharmacology. 38(11):2170-8.
2012
Sondhi D, Johnson L, Purpura K, Monette S, Souweidane MM, Kaplitt MG, Kosofsky B, Yohay K, Ballon D, Dyke J et al..  2012.  Long-term expression and safety of administration of AAVrh.10hCLN2 to the brain of rats and nonhuman primates for the treatment of late infantile neuronal ceroid lipofuscinosis.. Hum Gene Ther Methods. 23(5):324-35.
2008
Worgall S, Sondhi D, Hackett NR, Kosofsky B, Kekatpure MV, Neyzi N, Dyke JP, Ballon D, Heier L, Greenwald BM et al..  2008.  Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA.. Hum Gene Ther. 19(5):463-74.
2005
Arkin LM, Sondhi D, Worgall S, Suh LHyon K, Hackett NR, Kaminsky SM, Hosain SA, Souweidane MM, Kaplitt MG, Dyke JP et al..  2005.  Confronting the issues of therapeutic misconception, enrollment decisions, and personal motives in genetic medicine-based clinical research studies for fatal disorders.. Hum Gene Ther. 16(9):1028-36.
2004
Crystal RG, Sondhi D, Hackett NR, Kaminsky SM, Worgall S, Stieg P, Souweidane M, Hosain S, Heier L, Ballon D et al..  2004.  Clinical protocol. Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis.. Hum Gene Ther. 15(11):1131-54.